Giuseppe Calamita Selected Research

Aquaglyceroporins

1/2018	Aquaglyceroporins: Drug Targets for Metabolic Diseases?
11/2017	Lipopolysaccharide Modifies Glycerol Permeability and Metabolism in 3T3-L1 Adipocytes.
7/2015	Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice.
4/2011	Insulin- and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3K/Akt/mTOR signaling cascade.

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Giuseppe Calamita Research Topics

Disease

9	Non-alcoholic Fatty Liver Disease 07/2021 - 09/2007
6	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 06/2011
6	Obesity 04/2021 - 04/2011
5	Fatty Liver 07/2021 - 06/2011
3	Fibrosis (Cirrhosis) 07/2021 - 06/2011
3	Metabolic Diseases (Metabolic Disease) 01/2018 - 01/2015
3	Cholestasis 05/2010 - 03/2007
2	Sepsis (Septicemia) 01/2022 - 05/2014
2	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021 - 06/2011
2	Alcoholic Fatty Liver 07/2021 - 07/2015
2	Liver Diseases (Liver Disease) 07/2021 - 06/2011
2	Inflammation (Inflammations) 01/2020 - 01/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 04/2011
2	Hypertension (High Blood Pressure) 01/2019 - 01/2018
2	Body Weight (Weight, Body) 01/2019 - 07/2015
2	Neoplasms (Cancer) 11/2017 - 11/2017
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2014 - 01/2013
2	Starvation 06/2012 - 02/2012
2	Extrahepatic Cholestasis 10/2008 - 05/2003
2	Cholelithiasis 06/2005 - 03/2003
1	Skin Diseases (Skin Disease) 04/2022
1	Coinfection 01/2022
1	Hypothermia 01/2022
1	Multiple Organ Failure (MODS) 01/2022
1	Cardiomyopathies (Cardiomyopathy) 01/2022
1	Endotoxemia 01/2021
1	Septic Shock (Toxic Shock Syndrome) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Hypertrophy 01/2019
1	Heart Failure 01/2019
1	Male Infertility (Male Sterility) 09/2018
1	Frailty 01/2018
1	Colitis 01/2018
1	Atherosclerosis 01/2018
1	Insulin Resistance 01/2015
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2014
1	Autoimmune Diseases (Autoimmune Disease) 05/2014
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 05/2014
1	Hepatic Encephalopathy 05/2013
1	Hyperammonemia 05/2013
1	Digestive System Diseases 10/2012

Drug/Important Bio-Agent (IBA)

10	Glycerol (Glycerine)FDA LinkGeneric 01/2020 - 04/2011
8	Proteins (Proteins, Gene)FDA Link 04/2022 - 05/2003
6	Aquaporins (Water Channels)IBA 04/2022 - 05/2003
5	Triglycerides (Triacylglycerol)IBA 01/2021 - 06/2011
5	LipidsIBA 01/2020 - 03/2003
5	Bile Acids and Salts (Bile Acids)IBA 11/2017 - 03/2003
4	Ion Channels (Ion Channel)IBA 04/2022 - 01/2013
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 05/2014
4	LeptinIBA 04/2021 - 04/2011
4	AquaglyceroporinsIBA 01/2018 - 04/2011
3	Pharmaceutical PreparationsIBA 01/2022 - 01/2018
3	Estrogens (Estrogen)FDA Link 04/2020 - 03/2007
2	NF-kappa B (NF-kB)IBA 01/2021 - 03/2020
2	PalmitatesIBA 04/2020 - 01/2020
2	Oleic Acid (Oleate)IBA 04/2020 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2020 - 03/2007
2	Therapeutic UsesIBA 11/2017 - 11/2017
2	AmmoniaIBA 05/2014 - 05/2013
2	Taurodeoxycholic AcidIBA 05/2007 - 03/2003
2	CholesterolIBA 06/2005 - 03/2003
1	RG100204IBA 01/2022
1	EndotoxinsIBA 01/2022
1	Superoxides (Superoxide)IBA 01/2022
1	Methionine (L-Methionine)FDA Link 07/2021
1	octanoic acid (caprylic acid)IBA 07/2021
1	IsotopesIBA 07/2021
1	AcidsIBA 07/2021
1	Sterol Regulatory Element Binding Protein 1IBA 01/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021
1	Phytoestrogens (Phytoestrogen)IBA 04/2020
1	AMP-Activated Protein KinasesIBA 04/2020
1	InflammasomesIBA 04/2020
1	GenisteinIBA 04/2020
1	Estradiol (Delestrogen)FDA LinkGeneric 04/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2020
1	Nonesterified Fatty Acids (NEFA)IBA 03/2020
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2020
1	Silybin (Lagosa)IBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2019
1	SaltsIBA 01/2019
1	Sulfates (Sulfates, Inorganic)IBA 01/2019
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2019
1	4-methylcatecholIBA 01/2019
1	PolyphenolsIBA 01/2019
1	CytokinesIBA 01/2018
1	PhytochemicalsIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Biomarkers (Surrogate Marker)IBA 10/2014
1	CarbohydratesIBA 10/2014
1	MucinsIBA 10/2014
1	LectinsIBA 10/2014
1	Sulfhydryl Compounds (Thiols)IBA 05/2014
1	Membrane LipidsIBA 05/2014
1	Voltage-Dependent Anion ChannelsIBA 01/2013
1	NADH oxidaseIBA 01/2013

Therapy/Procedure

2	Ligation 01/2022 - 05/2010
2	Therapeutics 01/2021 - 09/2007
1	Oral Administration 01/2022
1	Punctures 01/2022